Wine related articles
Red Wine, an Efficient Weapon against Alzheimer's
The Pinot Noir wine is the most recommended
By:
Tudor Raiciu, World and Health News Editor
After discovering Bryostatin’s benefic effects on Alzheimer’s, the
researchers announced that the red wine might also be an efficient
remedy.
A new study shows that resveratrol, a compound found in grapes and red
wine, lowers the levels of the amyloid-beta peptides, which are
responsible for the disease.
"Resveratrol is a natural polyphenol occurring in abundance in several
plants, including grapes, berries and
peanuts. The polyphenol is found in high concentrations in red wines.
The highest concentration of resveratrol has been reported in wines
prepared from Pinot Noir grapes”, explains study author Philippe
Marambaud.
One of the characteristic features of Alzheimer’s disease is the
deposition of amyloid-beta peptides in the brain. Philippe Marambaud and
his colleagues at the Litwin-Zucker Research Center for the Study of
Alzheimer’s Disease and Memory Disorders in Manhasset, New York,
administered resveratrol to cells which produce human amyloid-beta and
tested the compound’s effectiveness by monitoring amyloid-beta levels
inside and outside the cells.
They found that levels of amyloid-beta in the treated cells were much
lower than those in untreated cells.
However, the discovery doesn’t imply that grapes alone constitute a
remedy for Alzheimer’s, the likelihood that the concentrations of
resveratrol in the fruit are insufficient high.
Following up on their studies, Marambaud and his colleagues are trying
to figure out how resveratrol exerts its effects in order to develop
similar compounds to use in fighting Alzheimer’s disease.
"Our long-term goal is now to elucidate the exact molecular mechanisms
involved in the beneficial properties of resveratrol as a necessary
prerequisite to the identification of novel molecular targets and
therapeutic approaches", said Dr. Marambaud.
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